This research aims to study the influence of different parameters such astypes of acid, acids concentration, reaction times, and liquid to solid ratio on the leaching process for phosphate ore. The hydrometallurgical method has been used for leaching phosphate ore after beneficiation with particle size 75-150 µm.The different acids HCl,H2NO3, Acetic acid, andH2SO4, were used with different concentration(0.5, 1, 1.5,2 and 4 M), solid toliquid ratio (2/100, 4/100, 6/100, 10/100, 20/100) ,acid concentration ranged (0.5, 1, 1.5,2 and 4 M), and the temperature range 25, 45, 65 and 85 °C at a stirring rate of 1200 rpm .XRD, and SEM used for phosphate ore inspection before leaching process. The best results represent byHCl when compared with the other acids, the hydrochloric acid concentration (4 M), solid to liquid ratio (2\100 g\l), temperature (85 °c), stirring speed (1200 rpm) and contact time (120 min.).