On the effect of toxic substances in small concentrations on the functional state of the organism, there are two main views. According to a number of authors [1, 2, 5, 6, 11, 12], under the influence of low intensity physical and chemical factors on the body as a result of training compensatory reactions, a state of nonspecific increased resistance is created. This article will elucidate medical state of people related to mining and metallurgy.